The Home Quadrants is the collective term for the Alpha and Beta Quadrants, one half of the entire Milky Way Galaxy and the main location of the United Federation of Planets. The boundary separating the Alpha and Beta Quadrants is defined by a meridian passing through the galactic core and at least near the Sol system.

Interstellar politics in the Home Quadrants in the late 24th century were generally dominated by the United Federation of Planets, along with other regional powers including the Klingon Empire, Romulan Star Empire, Cardassian Union, the Tzenkethi, the Talarian Republic, and the Ferengi Alliance, all of which interacted on generally peaceful terms. Members of the Tholian Assembly and the Breen Confederacy remained mostly isolated from the rest of the Alpha Quadrant populations.

While only about 50% of the the two quadrants sufficiently explored by Starfleet, the region is known to contain examples of shocking interstellar beauty and scientific wonder such as the Argolis Cluster, the Arachnid Nebula and the Cardassian Badlands.

Alpha and Beta Quadrants

Spanning a total distance of 240 lightyears, the home quadrants are home to thousands of species, with the most noted being the Breen Confederacy, Cardassian Union, Ferengi Alliance, Klingon Empire, Romulan Star Empire, Talarian Republic, Tzenkethi Coalition and the United Federation of Planets.